Waning immunity
Antibody kinetics, B-cell memory, T-cell persistence and the biological factors associated with changing protection over time.
Singapore · July 12–14, 2027
NULLIFY 2027 brings together the scientific, clinical, regulatory and public-health perspectives required to understand why protection fades—and how the next generation of vaccines can be designed, evaluated and deployed for more durable immunity.
The central question
Vaccine performance is not defined only by the initial immune response. The duration, quality and breadth of protection influence booster schedules, product differentiation, public confidence, health-system planning and the real-world impact of immunization programmes.
NULLIFY creates a focused environment for examining durability across immune memory, antigen and platform design, clinical endpoints, surveillance, regulation and implementation. It is a conference for people who need to connect mechanistic science with practical vaccine-development decisions.
Scientific and strategic themes
Antibody kinetics, B-cell memory, T-cell persistence and the biological factors associated with changing protection over time.
How immune markers, clinical endpoints and real-world evidence can support predictions about durability and effectiveness.
Approaches to antigen design, adjuvants, delivery systems and platform engineering intended to improve the quality or persistence of immunity.
Trial design, longitudinal follow-up, population differences and evidence strategies for measuring durable protection.
How regulators, public-health agencies and developers evaluate changing effectiveness, booster strategies and post-market evidence.
Translating durability evidence into immunization schedules, procurement decisions, communication and equitable access.
Who should attend
Event details
A vaccine durability conference examines why protection changes over time and how immune memory, antigen design, delivery, clinical evidence, surveillance and booster strategy can support longer-lasting protection.
NULLIFY covers waning immunity, antibody and T-cell persistence, immune memory, correlates of protection, next-generation platforms, clinical development, regulatory evidence and public-health implementation.
The summit is intended for immunologists, vaccine developers, clinicians, regulators, public-health leaders, academic researchers, technology partners and organizations developing or evaluating vaccines.
Join the durability conversation
Review delegate passes and secure access to NULLIFY 2027.