NULLIFY 2027 / Conference guide

Singapore · July 12–14, 2027

Vaccine durability and waning immunity conference.

NULLIFY 2027 brings together the scientific, clinical, regulatory and public-health perspectives required to understand why protection fades—and how the next generation of vaccines can be designed, evaluated and deployed for more durable immunity.

The central question

How do we build protection that holds?

Vaccine performance is not defined only by the initial immune response. The duration, quality and breadth of protection influence booster schedules, product differentiation, public confidence, health-system planning and the real-world impact of immunization programmes.

NULLIFY creates a focused environment for examining durability across immune memory, antigen and platform design, clinical endpoints, surveillance, regulation and implementation. It is a conference for people who need to connect mechanistic science with practical vaccine-development decisions.

Scientific and strategic themes

What the vaccine durability programme explores.

01

Waning immunity

Antibody kinetics, B-cell memory, T-cell persistence and the biological factors associated with changing protection over time.

02

Correlates of protection

How immune markers, clinical endpoints and real-world evidence can support predictions about durability and effectiveness.

03

Next-generation platforms

Approaches to antigen design, adjuvants, delivery systems and platform engineering intended to improve the quality or persistence of immunity.

04

Clinical development

Trial design, longitudinal follow-up, population differences and evidence strategies for measuring durable protection.

05

Regulation and policy

How regulators, public-health agencies and developers evaluate changing effectiveness, booster strategies and post-market evidence.

06

Implementation

Translating durability evidence into immunization schedules, procurement decisions, communication and equitable access.

Who should attend

A cross-functional vaccine audience.

  • Vaccine immunology and infectious-disease researchers
  • Clinical development, medical affairs and translational teams
  • Regulatory agencies, policy makers and public-health organizations
  • Pharmaceutical, biotechnology and platform-development leaders
  • Academic investigators, clinicians and epidemiologists
  • Diagnostics, data, CRO, manufacturing and technology partners

Event details

NULLIFY 2027 at a glance.

DatesJuly 12–14, 2027
LocationHilton Singapore Orchard, Singapore
ParticipationIn-person conference with virtual-access options
What is a vaccine durability conference?

A vaccine durability conference examines why protection changes over time and how immune memory, antigen design, delivery, clinical evidence, surveillance and booster strategy can support longer-lasting protection.

What topics does NULLIFY 2027 cover?

NULLIFY covers waning immunity, antibody and T-cell persistence, immune memory, correlates of protection, next-generation platforms, clinical development, regulatory evidence and public-health implementation.

Who should attend NULLIFY 2027?

The summit is intended for immunologists, vaccine developers, clinicians, regulators, public-health leaders, academic researchers, technology partners and organizations developing or evaluating vaccines.

Join the durability conversation

Connect vaccine science with decisions that affect protection.

Review delegate passes and secure access to NULLIFY 2027.